Understanding Attitudes to Genetic Risk for Cardiovascular Disease

This project aims to investigate how information about genetic risks for cardiovascular disease, conveyed through polygenic risk scores (PRS), influences individuals' decisions on further health investigations or treatments. A polygenic risk score summarises genetic contributions to the likelihood of developing certain diseases, offering a new avenue for personalised medicine in primary care.

Through a method known as a discrete choice experiment (DCE), the study will present participants with scenarios that vary in genetic risk levels, source of risk information (NHS or private company), and waiting times for test results. This approach will help quantify the impact of genetic risk information on people's healthcare choices.

The importance of this research lies in its potential to refine how genetic risk information is used in healthcare, making it more effective in preventing and managing diseases. By understanding public attitudes towards genetic risks, healthcare providers can better support individuals at higher risk of cardiovascular conditions, possibly leading to earlier interventions and improved health outcomes. This project not only advances scientific knowledge but also has significant implications for patient care and health policy.