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Research groups

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Edoardo G. Ostinelli

MD, Psychiatrist, DPhil

Senior Researcher, OxPPL Deputy Lead

  • Senior Researcher & Deputy Lead, Oxford Precision Psychiatry Lab (OxPPL), Department of Psychiatry, University of Oxford
  • CRF Senior Medic, NIHR Oxford cognitive health Clinical Research Facility, Oxford Health NHS Foundation Trust, Oxford
  • Honorary Consultant Psychiatrist, Oxford Health NHS Foundation Trust, Oxford

My research focuses on the implementation of evidence-based medicine in real-world practice, developing and optimising both precision medicine and shared decision-making to ensure people's voice is heard. I work closely with colleagues in precision medicine, statistics, and clinical decision-making (Universities of Bern, Kyoto, London, Munich, Ottawa, Tokyo, and Toronto).

I developed the PETRUSHKA web tool in collaboration with the Department of Computer Science. The PETRUSHKA tool is an online interactive clinical decision support system (CDSS) which seeks to individualise treatment with antidepressants for patients with depression, using 1) data from randomised controlled trials, 2) data from observational studies, and 3) preferences elicited in real-time by individual patients using the PETRUSHKA tool. I was the Lead Investigator in the UK for the randomised controlled trial evaluating the PETRUSHKA tool in the United Kingdom and Canada. Discover more on the PETRUSHKA trial here!

I also lecture on different subject areas related to psychiatry and research methodology for the MSc Clinical and Therapeutic Neuroscience Course within the University of Oxford; precision mental health at the Master in Evidence-based therapeutic approaches and evaluation methods for prevention and early intervention in mental health within the University of Verona; evidence synthesis methodology and how to perform basic and advanced meta-analysis on R at the Oxford Course on Systematic Review & Meta-Analysis for the University of Oxford; communication of benefit-risk information from network meta-analyses at the Oxford Course in Network Meta-Analysis for the University of Oxford.

Key publications

Recent publications